Friday, November 28, 2008

Universal Aging

More evidence today on the commonality of aging mechanisms across species. David Sinclair of Harvard Medical School and colleagues have demonstrated that similar proteins (of the sirtuin class) mitigate cell aging in yeast and mice. Sinclair is quoted in Technology Review: "Life, in general, has an Achilles heel, and this is it."

Sinclair is co-founder of Sirtris Pharmaceuticals, much in the news lately.

(image credit: SIRT1 protein (red) clusters around mouse chromosomes (blue). Phillip Oberdoerffer,